Payne Lab research focuses on understanding how nanomaterials interact with biological systems. This includes fundamental questions of nanoparticle-protein interactions, as well as applied research to understand the pulmonary response to the inhalation of nanoparticles in a manufacturing setting. The team uses an interdisciplinary approach that includes elements of materials science, chemistry, biophysics, and lab automation. Students in the Payne Lab develop expertise in fluorescence microscopy, electron microscopy, fluorescence and UV-Vis spectroscopy, dynamic light scattering, cell culture, and molecular biology.

The Payne Lab is recruiting undergraduate researchers, PhD students (Fall 27), and postdocs. Undergraduates and postdocs should email Prof. Payne a copy of their resume/CV, a brief cover letter, and the names of 3 references. PhD students can apply to the lab through Duke's Graduate School (deadline: mid-December 2026).